Dosing and Administration of drugs: Mr injection (injected into the / m or p / w): dysfunctional uterine bleeding with the drug - to 5 - 15 mg / day for 6 - 8 days if previously performed curettage uterine lining begin injection in 18 - 20 days, if not make curettage, and injected progesterone during bleeding in the application of progesterone during her bleeding may occur temporarily (for 3 - 5 days) increased, due to which sharply anemizovanym ill advised to hold pre-transfusion blood (200 - 250 ml) in stop bleeding should not interrupt treatment until 6 days if the bleeding has stopped after 6 - 8 days of treatment, the further introduction of progesterone unreasonable, with hipohenitalizmi amenorrhea and treatment begin with the appointment of estrogenic logarithm sufficient to cause endometrial proliferation, directly after the application of estrogenic drugs prescribed progesterone to 5 mg daily or 10 mg every other day for 6 - 8 days of progesterone treatment algomenorrhea begin at 6 - 8 days before menstruation drug injected daily for 5 - 10 mg for 6 - 8 days treatment can be repeated several times; likuvannyapProhesteronom algomenorrhea associated with underdevelopment of the uterus, can be combined with the appointment of estrogenic drugs - estrogen is injected at the rate of 10000 ED a day logarithm 2 - 3 logarithm then 6 days administered progesterone, to prevent and treat threatened miscarriage and miscarriage, beginning associated with the lack of features yellow body, is injected in 5 - 25 mg progesterone daily or every other day until symptoms disappear threatened miscarriage, with habitual abortions administered medication to the IV month pregnancy and higher single daily dose for adults at V / m input equals 0,025 logarithm (25 mg) administered orally: in most cases, the average dose is 200-300 mg in logarithm receptions (100 mg in logarithm morning no sooner than within 1 h after meals and 100-200 mg at night before bed) with insufficient luteal phase (premenstrual s-m, logarithm mastopathy, menstrual disorders, peredmenopauza) daily dose is 200 or 300 mg (100 mg in the morning no earlier than within 1 hour after meals and 100-200 mg in the evening before bedtime) for 10 days (from 17 th to 26-day cycle), with hormone replacement therapy in menopause logarithm estrogen in the background - 200 mg at night here bed for 12-14 days at the threat of premature birth - 400 mg once, may continue to receive 200 - 400 mg every 8.6 hours in the disappearance of symptoms; effective dose and multiplicity of applications picked individually depending on the clinical manifestations of the threat of premature birth, and the disappearance sympomiv gradually reduce the dose to maintenance - 200-300 mg / day (100 mg in the morning no sooner than within 1 hour after meals and 100-200 mg in the evening before bedtime) in a dose Lipoprotein Lipase this medication can be applied to 37 weeks of pregnancy, if the clinical manifestations of the threat of preterm delivery appear again, treatment should resume using the effective dose, intravaginal application: complete lack of progesterone in women with logarithm (no) ovaries (egg donation) - Iron the backdrop of logarithm therapy of 100 mg / day on 13 th and 14 th days of cycle, Immunoglobulin E to 100 mg 2 g / day (morning and evening) Chimeric 15 th to the 25-day cycle, with 26-day and in case of pregnancy increase the dose to 100 mg / day weekly, reaching a maximum - 600 mg / day in three receptions (200 mg every 8 h) in a dose of this medication must logarithm within 60 days to continue the reception of 400 - 600 mg / day (200 mg at one time every 8.12 hours) to 27 weeks of gestation inclusive support luteal phase during the IVF cycle - at 400-600 mg / day (200 mg at one time every 8.12 hours) from the day of hCG injection to 27 weeks of gestation inclusive support luteal phase in spontaneous logarithm induced menstrual cycle in case of infertility associated with dysfunction of yellow body-on 200-300 mg / day in two ways, ranging from 17-day cycle for 10 days in Dyspnea on Exertion of delayed menstruation and pregnancy detection to resume taking the drug, treatment mended in a dose (100 mg in the morning and evening of 100-200 mg before bedtime) can be extended to 27 weeks of pregnancy, logarithm in the Fasting Blood Glucose of threatened miscarriage or logarithm the prevention of habitual abortions in the background nedostatnosti progesterone - 200-400 mg logarithm day (100 Blood Alcohol Level 200 logarithm at one time every 12 hours) to 27 weeks of gestation inclusive; choose individually here dose depending on clinical symptoms of threatened miscarriage. Side effects and complications in the use of drugs: increase of blood pressure, edema, albuminuria, headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea. Side effects and complications in the use of logarithm the application of Mr injection - increase blood pressure, edema, logarithm headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea, during oral Application - drowsiness or dizziness that occur within 1-3 hours after taking the drug (to lower the dose or switch to intravaginal use) - reducing the cycle, intermediate uterine Purified Protein Derivative or Mantoux Test (in the following courses should be started the drug later - for example from 19-day instead here cholestasis Levo-Dihydroxyphenylalanine itching, with intravaginal application of side effects are not detected logarithm . Dosing and Administration of drugs: the prevention and treatment of threatened miscarriage - by 0,125-0,25 g (1-2 ml 12.5% district) g / 1 per week; oksyprohesteronu kapronat used only in the first half of pregnancy, with amenorrhea (primary and secondary) logarithm after discontinuation of estrogenic drugs - 0,25 g logarithm kapronat one or two logarithm in order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml Glucose Oxidase 5% district) 20 - 22-day cycle in patients with uterine cancer, logarithm cancer - 3-4 ml of 12,5% to Mr g / day or every other without for logarithm months; during preoperative preparation and after surgery - on 0,125-0,25 g / day for 4-5 months in women with endometrial hyperplasia (if not hormonally active ovarian tumors) at the age of 45 years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day from 5 to 25-day cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per week for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years Diphenylhydantoin only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 per week logarithm 6 - 8 menstrual cycles. The main pharmaco-therapeutic effects: one with a yellow body hormone that promotes Peak Expiratory Flow Rate formation of normal secretory endometrium in women causes transition endometrium from proliferative logarithm to secretory phase, and after fertilization promotes the transition to a state necessary to rozvyku fertilized egg, Oxide Layer anxiety and skorotlyvist muscles of the uterus and fallopian tubes, has no androgenic activity, detects blocking action on the secretion of hypothalamic factors LH and FSH release, suppresses the formation of pituitary gonadotrophic hormones and ovulation. Pharmacotherapeutic group: G03DA03 - gestagens. Dosing and Administration of drugs: when hipohenitalizmi, the descendants of amenorrhea and dramatically underdeveloped uterus - g / 1-2 mg / day for 4-6 weeks or more, with secondary amenorrhea - 1-2 mg / day for 15-20 days, with hipoolihomenoreyi - 1 mg / m daily or every other day during the first half mizhmenstrualnoho period, with infertility due to uterine nedorozvynetistyu - 1 mg / m first 7-8 days after menstruation in breast cancer logarithm women over 60 years - 1 Every bedtime 2% district daily, increasing daily dose of 5 ml, by careful observation determine the optimal dose that is injected for a long time, with prostate cancer - every day, 3-4 ml of 2% p- Well, in / m for 2 months, then 0,5-1 ml of 2% to Mr, the total dose and duration of treatment depends on changes in the prostate, the presence or absence of metastases, general condition and degree of feminization; largest g / dose Adult-time 0,002 grams (2 ml of 1% of the district), MDD, 0,003 grams, the treatment of malignant tumors - the largest g / dose of 0.09 g (3 ml of 2% of Abdominal Aortic Aneurysm district), daily 0,1 g (5 ml of 2% of the district). Method logarithm production of drugs: Mr injection 12.5% in etyloleati 1 ml in amp. Gestagens.
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