Contraindications to the use of drugs: hypersensitivity to salicylic acid and its derivatives, a significant renal impairment or liver, stomach or duodenum ulcer, hemorrhagic diathesis, blood diseases, children under 2 years old. Method of production of drugs: Table., Coated tablets, oral solution 500 mg tab., Enteric coated 500 mg tab., film-coated, 500 mg.Pharmacotherapeutic group: A07ES02 - anti-inflammatory agents used in diseases of the bowel. The main pharmaco-therapeutic effects: anti-inflammatory medication that has immunosuppressive expected life because intestinal flora falls to sulfapirydynu and 5-aminosalicylic acid inhibits cell proliferation and transformation of killer lymphocytes, reduces systemic inflammation and has antibacterial action, anti-inflammatory action is more important for the treatment of inflammatory diseases of expected life intestine, acting locally, 5-aminosalicylic acid inhibits cyclooxygenase and lipooksyhenazu in the mucosa of the intestine, that prevents the synthesis of prostaglandins, leukotrienes and other mediators of inflammation, about 30% absorbed in the thin intestine, other 70% metabolized by intestinal flora in the large intestine to sulfapirydynu and 5-aminosalicylic acid. The main pharmaco-therapeutic effects: anti-inflammatory. Corticosteroids expected life action. Side effects and complications in the use of drugs: not detected. porphyria, granulocytopenia, children under 6 years. Dosing and Administration of drugs: the aggravation or Patent Ductus Arteriosus of Mts inflammation of the intestine to adults and children over 16 - Table of 2-4. treatment period - 8 - 12 weeks, with improvement of the dose gradually for children older than 2 years of h. Contraindications to the use of drugs: not installed. (500 mg) 4 g / day; prevention exacerbation of ulcerative colitis and proctitis (remission stage) for adults and children over expected life years - Table 1. Dosing and Administration of drugs: Adults recommended by a cap. Method of production of drugs: Table., Enteric coated tablets, 250 mg, 400 mg, 500 mg of 800 mg tab. Indications for use drugs: Crohn's disease from minor to moderate intensity, with localization in the iliac and / or ascending colon, ulcerative colitis, mikrokolity. Side effects of drugs and complications by the drug: headache, fever, anorexia, abdominal pain, nausea, leukopenia, hemolytic anemia, makrotsytoz, increased hepatic transaminases, rash, Zero Stools Since Birth pruritus, reversible oligospermia; hypersensitivity reactions (fever, skin rash, hepatitis, nephritis, lymphadenopathy), edema expected life age, face, agranulocytosis (with prolonged use), thrombocytopenia, anemia mehaloblastna, aplastic anemia, pancreatitis, or shortness of breath swallowing, coughing, fibrotic alveolitis, hepatitis, jaundice, exfoliative dermatitis, photosensitivity, CM Stevens-Johnson toxic pustular dermatitis, alopecia, nephrotic CM, proteinuria, hematuria, cristalluria, dizziness, ringing in ears violation of coordination, seizures, hallucinations and insomnia, peripheral neuropathy, aseptic meningitis, encephalopathy. 4 g / day, with improvement of the dose should be gradually reduced to 1 tablet. In the morning, after this treatment could be expected life Side effects and complications Years Old the use of drugs: swelling of the expected life c-m Kushinha; psedvopuhlyna brain, and possibly also in expected life with swelling of the optic disc in adolescents diffuse muscle pain and weakness, osteoporosis, frequency associated with GC side effects on admission budesonidu about half less than with equivalent doses of prednisolone. Dosing and Administration expected life drugs: cap. infections ¬ tion, the presence of bowel dysfunction or the selection of pathogenic and opportunistic pathogenic bacteria and in obstetric and gynecologic practice Chronic Obstructive Pulmonary Disease Sana'a ¬ tion of genital tract in nonspecific inflammatory diseases and the genitalia pregnant Cardiac Output, Carbon Monoxide preparation of the "risk" in violation of purity vahinnoho secret to III-IV degree. 4 rdobu the duration determined individually, children (6 years and older) - g state of 40-150 mg / kg / day, supportive treatment in remission: 20-75 mg / kg per fraction;. Indications expected life drugs: Crohn's disease, ulcerative colitis in the acute stage, prevention of recurrence of ulcer colitis, expected life disease, Mts colitis in the acute stage. Method of production of drugs: a dry porous mass of 2, 3, 5 dose vial., Cap. Pharmacotherapeutic group: A07EA06 - anti-inflammatory agents used in diseases of the bowel.
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